Benadryl Injection (Diphenhydramine Injection) Drug Information: Overdosage and Contraindications

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May 25, 2012

Benadryl Injection

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Scabies facts

Scabies is an itchy, highly contagious skin condition caused by an infestation by the itch mite Sarcoptes scabiei.
Direct skin-to-skin contact is the mode of transmission.
A severe and relentless itch is the predominant symptom of scabies.
Sexual contact is the most common form of transmission among sexually active young people, and scabies has been considered by many to be a sexually transmitted disease (STD).
Scabies produces a skin rash composed of small red bumps and blisters and affects specific areas of the body.
Treatment includes oral or topical scabicidal drugs.

What is scabies?

Scabies is an itchy, highly contagious skin disease caused by an infestation by the itch mite Sarcoptes scabiei. Mites are small eight-legged parasites (in contrast to insects, which have six legs). They are tiny, just 1/3 millimeter long, and burrow into the sk...

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OVERDOSE

Antihistamine overdosage reactions may vary from central nervous system depression to stimulation. Stimulation is particularly likely in pediatric patients. Atropine-like signs and symptoms; dry mouth; fixed, dilated pupils; flushing; and gastrointestinal symptoms may also occur. Stimulants should not be used.

Vasopressors may be used to treat hypotension.

CONTRAINDICATIONS

Use in Neonates or Premature Infants

This drug should not be used in neonates or premature infants.

Use in Nursing Mothers

Because of the higher risk of antihistamines for infants generally, and for neonates and prematures in particular, antihistamine therapy is contraindicated in nursing mothers.

Use as a Local Anesthetic

Because of the risk of local necrosis, this drug should not be used as a local anesthetic.

Antihistamines are also contraindicated in the following conditions: Hypersensitivity, to diphenhydramine hydrochloride and other antihistamines of similar chemical structure.

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.