"SAN DIEGO, California â€” A novel liposomal formulation of cytarabine and daunorubicin, known as CPX-351 (Vyxeos, Jazz Pharmaceuticals), has again been shown to be superior to a standard version of this combination, the 7+3 regimen of cytara"...
(bendamustine hydrochloride) Injection
BENDEKA (bendamustine hydrochloride) injection is an alkylating agent. The chemical name of bendamustine hydrochloride is 1H-benzimidazole-2-butanoic acid, 5-[bis(2chloroethyl)amino]-1 methyl-, monohydrochloride. Its empirical molecular formula is C16H21Cl2N3O2 • HCl, and the molecular weight is 394.7. Bendamustine hydrochloride contains a mechlorethamine group and a benzimidazole heterocyclic ring with a butyric acid substituent, and has the following structural formula:
BENDEKA (bendamustine hydrochloride) injection is supplied as a sterile, clear, and colorless to yellow ready-to-dilute solution in a multiple-dose clear glass vial. Each milliliter contains 25 mg of bendamustine hydrochloride, 0.1 mL of Propylene Glycol, USP, 5 mg of Monothioglycerol, NF, in Polyethylene Glycol 400, NF. Sodium hydroxide may have been used to adjust the acidity of polyethylene glycol 400.
Last reviewed on RxList: 2/24/2017
This monograph has been modified to include the generic and brand name in many instances.
Additional Bendeka Information
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