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Angiotensin Receptor Blockers (ARBs) »
The class of drugs called angiotensin receptor blockers (ARBs), as the class name suggests, are drugs that block the action of angiotensin. Specifically, ARBs prevent angiotensin II from binding to the angiotensin II receptor on blood vessels and other tissues.
Angiotensin II is a very potent chemical that causes the muscles surrounding blood vessels to contract, thereby narrowing the blood vessels. Narrowing of blood vessels increases the pressure within the blood vessels and may lead to high blood pressure (hypertension). Reducing the binding and activity of angiotensin II leads to widening (dilation) of blood vessels and reduces blood pressure. By lowering blood pressure against which the heart must pump, the amount of work that the heart must do is reduced. ACE inhibitors also reduce blood pressure in the kidneys, slowing the progression of kidney disease due to high b...
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Medical Editor: Charles Patrick Davis, MD, PhD
Benicar (olmesartan medoxomil) is an angiotensin II receptor antagonist used to reduce and control hypertension (high blood pressure). Generic Benicar is available outside of the US as olmesartan medoxomil. Common side effects of Benicar include dizziness, bronchitis, back pain, headache, flu-like symptoms, hematuria, and sinusitis.
Benicar is available in strengths of 5, 20, or 40 mg of olmesartan medoxomil tablets. The usual recommended starting dose is 20 mg per day but dosage in pediatric patients needs to be calculated for each individual. Potentially serious side effects include difficulty with breathing or swallowing, chest pain, cough, vertigo, abdominal pain, hyperkalemia, renal failure, and rhabdomyolysis. Benicar should not be used in pregnancy due to possible fetal damage or death; lactating women and their doctors need to weigh the advantages vs the possible harm if the drug is used. There is only one study in pediatric patients (ages 1-16 years) that suggests that Benicar is well tolerated with similar side effects seen in adults.
Our Benicar Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and conditions.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Benicar is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including the class to which this drug principally belongs. There are no controlled trials demonstrating risk reduction with Benicar.
Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as a...
Read the complete drug monograph for Benicar »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, olmesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.
Call your doctor at once if you have any other serious side effect, such as:
Read the complete patient information for Benicar »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it...
Read the complete consumer information for Benicar »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips on handling your hypertension.