font size

Benzodiazepines (cont.)

Pharmacy Author:
Medical Editor:

Are there differences between benzodiazepines?

Benzodiazepines differ in how quickly they start working, how long they continue to work, and for what they are most commonly prescribed.

  • Diazepam (Valium) and clorazepate (Tranxene) have fast onsets of action and usually start working within 30 to 60 minutes.
  • Oxazepam (Serax) has a slow onset, and lorazepam (Ativan), alprazolam (Xanax), and clonazepam (Klonopin) have intermediate onsets of action.
  • Clorazepate (Tranxene), midazolam (Versed), and triazolam (Halcion) are short-acting agents with durations of action of 3 to 8 hours.
  • Alprazolam (Xanax), lorazepam (Ativan), estazolam (Prosom), and temazepam (Restoril) are intermediate-acting agents with durations of action of 11 to 20 hours.
  • Chlordiazepoxide (Librium), clonazepam (Klonopin), diazepam (Valium), flurazepam (Dalmane), and quazepam are long-acting agents with duration of action of 1 to 3 days.

Although most benzodiazepines are used interchangeably, some are most commonly used for certain conditions.

  • Alprazolam (Xanax), chlordiazepoxide (Librium), chlorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), and midazolam are used for anxiety disorders.
  • Clonazepam (Klonopin), clorazepate (Tranxene), lorazepam (Ativan), clobazam (Onfi), and diazepam (Valium) are used for seizure disorders.
  • Estazolam (Prosom), flurazepam (Dalmane), quazepam (Doral), temazepam (Restoril), and triazolam (Halcion) are used for insomnia or trouble sleeping.
  • Midazolam (Versed), lorazepam (Ativan), and diazepam (Valium) are used in anesthesia.
  • Diazepam (Valium) also is used for muscle relaxation.
  • Chlordiazepoxide (Librium) is used for alcohol withdrawal.
Medically Reviewed by a Doctor on 4/2/2015


Emotional Wellness

Get tips on therapy and treatment.

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations