In this Article
- What other names is Berberine known by?
- What is Berberine?
- How does Berberine work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Berberine.
Cyclosporine (Neoral, Sandimmune)
Interaction Rating: Major Do not take this combination.
The body breaks down cyclosporine (Neoral, Sandimmune) to get rid of it. Berberine might decrease how fast the body breaks down cyclosporine (Neoral, Sandimmune). Cyclosporine (Neoral, Sandimmune) might build up in the body and could possible cause side effects.
Medications changed by the liver (Cytochrome P450 3A4 [CYP3A4] substrates)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.
Some medications are changed and broken down by the liver. Berberine might decrease how quickly the liver breaks down some medications. Taking berberine along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking berberine, talk to your healthcare provider if you are taking any medications that are changed by the liver.
Some medications changed by the liver include cyclosporin (Neoral, Sandimmune), lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), and many others.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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