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Betaxolol Hydrochloride Ophthalmic

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Betaxolol Hydrochloride Ophthalmic

Side Effects
Interactions

SIDE EFFECTS

The following adverse reactions have been reported in clinical trials with Betaxolol Hydrochloride Ophthalmic Solution (betaxolol hydrochloride) .

Ocular: Discomfort of short duration was experienced by one in four patients, but none discontinued therapy; occasional tearing has been reported. Rare instances of decreased corneal sensitivity, erythema, itching sensation, corneal punctate staining, keratitis, anisocoria, edema, and photophobia have been reported.

Additional medical events reported with other formulations of betaxolol include blurred vision, foreign body sensation, dryness of the eyes, inflammation, discharge, ocular pain, decreased visual acuity, and crusty lashes.

Systemic: Systemic reactions following administration of Betaxolol Hydrochloride Ophthalmic Solution 0.5% or Betaxolol Hydrochloride Ophthalmic (betaxolol hydrochloride) Suspension 0.25% have been rarely reported. These include:

Cardiovascular: Bradycardia, heart block and congestive failure.

Pulmonary: Pulmonary distress characterized by dyspnea, bronchospasm, thickened bronchial secretions, asthma and respiratory failure.

Central Nervous System: Insomnia, dizziness, vertigo, headaches, depression, lethargy, and increase in signs and symptoms of myasthenia gravis.

Other: Hives, toxic epidermal necrolysis, hair loss and glossitis.

Read the Betaxolol Hydrochloride Ophthalmic (betaxolol hydrochloride) Side Effects Center for a complete guide to possible side effects

DRUG INTERACTIONS

Patients who are receiving a beta-adrenergic blocking agent orally and Betaxolol Hydrochloride Ophthalmic Solution (betaxolol hydrochloride) should be observed for a potential additive effect either on the intraocular pressure or on the known systemic effects of beta blockade.

Close observation of the patient is recommended when a beta blocker is administered to patients receiving catecholamine-depleting drugs such as reserpine, because of possible additive effects and the production of hypotension and/or bradycardia.

Betaxolol is an adrenergic blocking agent; therefore, caution should be exercised in patients using concomitant adrenergic psychotropic drugs.

Ocular: In patients with angle-closure glaucoma, the immediate treatment objective is to reopen the angle by constriction of the pupil with a miotic agent. Betaxolol has little or no effect on the pupil. When Betaxolol Hydrochloride Ophthalmic Solution (betaxolol hydrochloride) is used to reduce elevated intraocular pressure in angle-closure glaucoma, it should be used with a miotic and not alone.

Last reviewed on RxList: 4/12/2006
This monograph has been modified to include the generic and brand name in many instances.

Side Effects
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