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No information is available on overdosage of humans. The oral LD50 of the drug ranged from 350-920 mg/kg in mice and 860-1050 mg/kg in rats. The symptoms which might be expected with an overdose of a systemically administered beta-1-adrenergic receptor inhibitor are bradycardia, hypotension and acute cardiac failure.
BETOPTIC S® (betaxolol hydrochloride ophthalmic suspension) Suspension is contraindicated in patients with:
- sinus bradycardia
- greater than a first degree atrioventricular block
- cardiogenic shock
- patients with overt cardiac failure
- hypersensitivity to any component of this product.
Last reviewed on RxList: 7/14/2008
This monograph has been modified to include the generic and brand name in many instances.
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