"The U.S. Food and Drug Administration today expanded the approved use of Stivarga (regorafenib) to treat patients with advanced gastrointestinal stromal tumors (GIST) that cannot be surgically removed and no longer respond to other FDA-approved t"...
- Patient Information:
Details with Side Effects
- To take premedications, including thyroid-blocking agents as prescribed [see WARNINGS AND PRECAUTIONS].
- To contact a healthcare professional if they experience signs and symptoms of allergic reactions [see WARNINGS AND PRECAUTIONS].
- To report to a health care professional any signs of cytopenias (bleeding, easy bruising, petechiae or purpura, pallor, weakness or fatigue, or symptoms of infection such as fever) [see WARNINGS AND PRECAUTIONS].
- Of the need for frequent monitoring for up to 3 months after treatment, and the potential for persistent cytopenias beyond 3 months.
- Concerning the risk of radiation exposure to household contacts, pregnant women and small children from radioactive materials remaining in the patient's body following the BEXXAR therapeutic regimen. Provide patient-specific advice orally and in writing [see WARNINGS AND PRECAUTIONS].
- Of the need for life-long monitoring for hypothyroidism [see WARNINGS AND PRECAUTIONS].
- Who are pregnant that the BEXXAR therapeutic regimen can cause hypothyroidism in the infant [see WARNINGS AND PRECAUTIONS, Use in Special Populations].
- To check with their physicians before receiving live virus vaccinations [see WARNINGS AND PRECAUTIONS].
- Who are of reproductive potential to use effective contraceptive methods during treatment and for a minimum of 12 months following the BEXXAR therapeutic regimen [see Use in Special Populations].
- To discontinue nursing during and after the BEXXAR therapeutic regimen [see Use in Special Populations].
Last reviewed on RxList: 9/27/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Bexxar Information
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