July 24, 2016
Recommended Topic Related To:

Biaxin

"If you've ever become sick after eating a food contaminated with disease-causing bacteria, it's not an experience you want to repeat.

But if you're part of what is called an "at-risk" or "vulnerable" population, a foodborne illness can be"...

A A A

Biaxin, Biaxin XL




Overdosage
Contraindications

OVERDOSE

Overdosage of BIAXIN can cause gastrointestinal symptoms such as abdominal pain, vomiting, nausea, and diarrhea.

Treat adverse reactions accompanying overdosage by the prompt elimination of unabsorbed drug and supportive measures. As with other macrolides, BIAXIN serum concentrations are not expected to be appreciably affected by hemodialysis or peritoneal dialysis.

CONTRAINDICATIONS

Hypersensitivity

BIAXIN is contraindicated in patients with a known hypersensitivity to clarithromycin, erythromycin, or any of the macrolide antibacterial drugs [see WARNINGS AND PRECAUTIONS].

Cardiac Arrhythmias

Concomitant administration of BIAXIN with cisapride and pimozide is contraindicated [see DRUG INTERACTIONS].

There have been postmarketing reports of drug interactions when clarithromycin is coadministered with cisapride or pimozide, resulting in cardiac arrhythmias (QT prolongation, ventricular tachycardia, ventricular fibrillation, and torsades de pointes) most likely due to inhibition of metabolism of these drugs by BIAXIN. Fatalities have been reported.

Cholestatic Jaundice/Hepatic Dysfunction

BIAXIN is contraindicated in patients with a history of cholestatic jaundice or hepatic dysfunction associated with prior use of clarithromycin.

Colchicine

Concomitant administration of BIAXIN and colchicine is contraindicated in patients with renal or hepatic impairment.

HMG-CoA Reductase Inhibitors

Do not use BIAXIN concomitantly with HMG-CoA reductase inhibitors (statins) that are extensively metabolized by CYP3A4 (lovastatin or simvastatin), due to the increased risk of myopathy, including rhabdomyolysis [see WARNINGS AND PRECAUTIONS and DRUG INTERACTIONS].

Ergot Alkaloids

Concomitant administration of clarithromycin and ergotamine or dihydroergotamine is contraindicated [see DRUG INTERACTIONS].

Contraindications For Co-administered Drugs

For information about contraindications of other drugs indicated in combination with BIAXIN, refer to their full prescribing information (contraindications section).

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 6/28/2016

Overdosage
Contraindications

Biaxin, Biaxin XL - User Reviews

Biaxin, Biaxin XL User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Biaxin, Biaxin XL sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.