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Brand Names: Bicillin C-R, Bicillin C-R 900/300

Generic Name: benzathine penicillin and procaine penicillin (Pronunciation: BENZ a theen PEN i SIL in and PRO kane PEN i SIL in)

• What is benzathine penicillin and procaine penicillin (Bicillin C-R Tubex)?
• What are the possible side effects of benzathine penicillin and procaine penicillin (Bicillin C-R Tubex)?
• What is the most important information I should know about benzathine penicillin and procaine penicillin (Bicillin C-R Tubex)?
• What should I discuss with my health care provider before using benzathine penicillin and procaine penicillin (Bicillin C-R Tubex)?
• How is benzathine penicillin and procaine penicillin given (Bicillin C-R Tubex)?
• What happens if I miss a dose (Bicillin C-R Tubex)?
• What happens if I overdose (Bicillin C-R Tubex)?
• What should I avoid while using benzathine penicillin and procaine penicillin (Bicillin C-R Tubex)?
• What other drugs will affect benzathine penicillin and procaine penicillin (Bicillin C-R Tubex)?
• Where can I get more information?

What is benzathine penicillin and procaine penicillin (Bicillin C-R Tubex)?

Benzathine penicillin and procaine penicillin is an antibiotic that fights bacteria in your body.

Benzathine penicillin and procaine penicillin is used to treat many different types of severe infections, including strep and staph infections, diphtheria, meningitis, gonorrhea, and syphilis.

Benzathine penicillin and procaine penicillin is also used to prevent infections of the heart valves in people with certain heart conditions who need to have dental work or surgery.

Benzathine penicillin and procaine penicillin may also be used for other purposes not listed in this medication guide.

What are the possible side effects of benzathine penicillin and procaine penicillin (Bicillin C-R Tubex)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
• skin rash with bruising, severe tingling, numbness, pain, muscle weakness;
• rash or itching with swollen glands, joint pain, or general ill feeling;
• diarrhea that is watery or bloody;
• slow heart rate, weak pulse, fainting, slow breathing;
• fast or pounding heartbeats;
• uncontrolled muscle movements, problems with vision, speech, balance, thinking, or walking;
• confusion, agitation, hallucinations, unusual thoughts or behavior;
• easy bruising or bleeding, unusual weakness;
• pale or yellowed skin, dark colored urine; or
• urinating less than usual or not at all.

Less serious side effects may include:

• nausea, vomiting;
• blurred vision, ringing in your ears;
• headache, dizziness;
• mild skin rash; or
• pain, swelling, bruising, skin changes, or a hard lump where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about benzathine penicillin and procaine penicillin (Bicillin C-R Tubex)?

You should not use this medication if you are allergic to penicillin. Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic such as Ceftin, Cefzil, Omnicef, Keflex, and others.

Before using benzathine penicillin and procaine penicillin, tell your doctor if you have asthma or a history of allergies, liver disease, kidney disease, or heart disease.

Do not inject this medication into a vein or life-threatening side effects may result.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Benzathine penicillin and procaine penicillin will not treat a viral infection such as the common cold or flu.

After you have finished your treatment with benzathine penicillin and procaine penicillin, your doctor may want to do tests to make sure your infection has completely cleared up.