Black Hellebore

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Are there any interactions with medications?



Antibiotics (Macrolide antibiotics)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Black hellebore can affect the heart. Some antibiotics might increase how much black hellebore the body absorbs. Taking black hellebore along with some antibiotics might increase the effects and side effects of black hellebore.

Some of these antibiotics, called macrolide antibiotics, include erythromycin, azithromycin, and clarithromycin.



Antibiotics (Tetracycline antibiotics)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Taking antibiotics along with black hellebore might increase the chance of side effects from black hellebore.

Some antibiotics that interact with black hellebore include demeclocycline (Declomycin), minocycline (Minocin), and tetracycline (Achromycin).



Digoxin (Lanoxin)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Digoxin (Lanoxin) helps the heart beat more strongly. Black hellebore also seems to affect the heart. Taking black hellebore along with digoxin can increase the effects and the risk of side effects of digoxin and black hellebore. Do not take black hellebore if you are taking digoxin (Lanoxin) without talking to your healthcare professional.



Quinine
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Black hellebore can affect the heart. Quinine can also affect the heart. Taking quinine along with black hellebore might cause serious heart problems.



Stimulant laxatives
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Black hellebore can affect the heart. The heart uses potassium. Laxatives called stimulant laxatives can decrease potassium levels in the body. Low potassium levels can increase the chance of side effects from black hellebore.

Some stimulant laxatives include bisacodyl (Correctol, Dulcolax), cascara, castor oil (Purge), senna (Senokot), and others.



Water pills (Diuretic drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Black hellebore might affect the heart. "Water pills" can decrease potassium in the body. Low potassium levels can also affect the heart and increase the risk of side effects from black hellebore.

Some "water pills" that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Microzide), and others.

Dosing considerations for Black Hellebore.

The appropriate dose of black hellebore depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for black hellebore. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.


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