Blenoxane (Bleomycin Sulfate Injection) Patient Information: Side Effects and Drug Images at RxList

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May 25, 2012

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Raynaud's Phenomenon »

What is Raynaud's phenomenon?

Raynaud's phenomenon (RP) is a condition resulting in a particular series of discolorations of the fingers and/or the toes after exposure to changes in temperature (cold or hot) or emotional events. Skin discoloration occurs because an abnormal spasm of the blood vessels causes a diminished blood supply to the local tissues. Initially, the digit(s) involved turn white because of the diminished blood supply. The digit(s) then turn blue because of prolonged lack of oxygen. Finally, the blood vessels reopen, causing a local "flushing" phenomenon, which turns the digit(s) red. This three-phase color sequence (white to blue to red), most often upon exposure to cold temperature, is characteristic of RP.

Raynaud's phenomenon most frequently affects women, especially in the second, third, or fourth decades of life. People can have Raynauds phenomenon alone or as a part of other rheumatic diseases. When it occurs alone...

Read the Raynaud's Phenomenon article »

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Blenoxane Patient Information Including Side Effects

Brand Names: Blenoxane

Generic Name: bleomycin (Pronunciation: BLEE oh MYE sin)

What is bleomycin (Blenoxane)?

Bleomycin is a cancer medication. Bleomycin interferes with the growth of cancer cells and slows their growth and spread in the body.

Bleomycin is used to treat squamous cell carcinoma, a skin cancer that can affect the mouth, throat, nose and sinuses, penis, vagina, cervix, and other. Bleomycin is also used to treat Hodgkin's disease and non-Hodgkin's lymphoma, testicular cancer, and malignant pleural effusion (a build-up of fluid in the outer tissues of the lungs, caused by certain types of cancer).

Bleomycin may also be used for other purposes not listed in this medication guide.

What are the possible side effects of bleomycin (Blenoxane)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

fever or chills;
sudden chest pain or discomfort, wheezing, dry cough or hack;
feeling short of breath on exertion;
chest discomfort, wheezing, dry cough or hack;
confusion, feeling weak or tired, loss of appetite, rapid weight loss;
feeling like you might pass out;
white patches or sores inside your mouth or on your lips;
severe redness, itching, rash, blistering, or tenderness of your skin; or
unusual hardening or thickening of your skin.

Less serious side effects may include:

dark streaks or discoloring on your skin;
fingernail or toenail changes;
temporary hair loss;
mild itching;
vomiting;
pain near your tumor; or
redness, warmth, itching, or swelling around the IV needle.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about bleomycin (Blenoxane)?

You should not receive bleomycin if you have ever had an allergic reaction to it.

Do not receive bleomycin without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

Before receiving bleomycin, tell your doctor if you have lung disease or a breathing disorder, kidney disease, or liver disease.

To be sure this medication is not causing harmful effects on your lungs, you may need to have chest X-rays or other lung function tests on a regular basis. Do not miss any follow-up visits to your doctor for X-rays or other tests.

If you need to have any type of surgery, tell the surgeon ahead of time that you are being treated with bleomycin.

Call your doctor at once if you have a serious side effect such as fever, chills, mouth sores, confusion, weakness, loss of appetite, rapid weight loss, sudden chest pain or discomfort, wheezing, dry cough, feeling short of breath, feeling like you might pass out, unusual hardening or thickening of your skin. or severe skin reaction (redness, itching, rash, blistering, or tenderness).

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