"Feb. 22, 2011 -- There is new evidence that long-term use of the most widely prescribed bone loss drugs may increase the risk for uncommon but serious femur (thigh bone) fractures.
In an analysis involving more than 200,000 postmenopa"...
No specific information is available on the treatment of overdosage of BONIVA. However, based on knowledge of this class of compounds, oral overdosage may result in hypocalcemia, hypophosphatemia, and upper gastrointestinal adverse events, such as upset stomach, dyspepsia, esophagitis, gastritis, or ulcer. Milk or antacids should be given to bind BONIVA. Due to the risk of esophageal irritation, vomiting should not be induced, and the patient should remain fully upright. Dialysis would not be beneficial.
- Abnormalities of the esophagus which delay esophageal emptying such as stricture or achalasia (see Upper Gastrointestinal Adverse Reactions)
- Inability to stand or sit upright for at least 60 minutes (see DOSING INSTRUCTIONS, Upper Gastrointestinal Adverse Reactions)
- Hypocalcemia (see WARNINGS AND PRECAUTIONS)
- Known hypersensitivity to BONIVA or to any of its excipients (see ADVERSE REACTIONS).
Last reviewed on RxList: 3/10/2011
This monograph has been modified to include the generic and brand name in many instances.
Additional Boniva Information
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