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No specific information is available on the treatment of overdosage of BONIVA. However, based on knowledge of this class of compounds, oral overdosage may result in hypocalcemia, hypophosphatemia, and upper gastrointestinal adverse events, such as upset stomach, dyspepsia, esophagitis, gastritis, or ulcer. Milk or antacids should be given to bind BONIVA. Due to the risk of esophageal irritation, vomiting should not be induced, and the patient should remain fully upright. Dialysis would not be beneficial.
BONIVA is contraindicated in patients with the following conditions:
- Abnormalities of the esophagus which delay esophageal emptying such as stricture or achalasia (see WARNINGS AND PRECAUTIONS)
- Inability to stand or sit upright for at least 60 minutes (see DOSAGE AND ADMINISTRATION, and WARNINGS AND PRECAUTIONS)
- Hypocalcemia (see WARNINGS AND PRECAUTIONS)
- Known hypersensitivity to BONIVA or to any of its excipients. Cases of anaphylaxis have been reported. (see ADVERSE REACTIONS).
Last reviewed on RxList: 1/8/2016
Additional Boniva Information
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