"The U.S. Food and Drug Administration today expanded the approved use of Imbruvica (ibrutinib) to treat patients with chronic lymphocytic leukemia (CLL) who carry a deletion in chromosome 17 (17p deletion), which is associated with poor responses"...
Bosulif Patient Information including If I Miss a Dose
In this Article
- What is bosutinib (Bosulif)?
- What are the possible side effects of bosutinib (Bosulif)?
- What is the most important information I should know about bosutinib (Bosulif)?
- What should I discuss with my healthcare provider before taking bosutinib (Bosulif)?
- How should I take bosutinib (Bosulif)?
- What happens if I miss a dose (Bosulif)?
- What happens if I overdose (Bosulif)?
- What should I avoid while taking bosutinib (Bosulif)?
- What other drugs will affect bosutinib (Bosulif)?
- Where can I get more information?
What happens if I miss a dose (Bosulif)?
Take the missed dose as soon as you remember. If you are more than 12 hours late, skip the missed dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Bosulif)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking bosutinib (Bosulif)?
Grapefruit and grapefruit juice may interact with bosutinib and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.
What other drugs will affect bosutinib (Bosulif)?
Many drugs can interact with bosutinib. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with bosutinib, especially:
- digoxin, digitalis;
- St. John's wort;
- an antibiotic--azithromycin, ciprofloxacin, clarithromycin, doxycycline, erythromycin, metronidazole, nafcillin, norfloxacin, rifabutin, rifampin, rifapentine, telithromycin, tetracycline;
- antifungal medication--clotrimazole, fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole;
- an antidepressant--desipramine, nefazodone, sertraline;
- heart or blood pressure medication--amiodarone, captopril, carvedilol, diltiazem, dronedarone, felodipine, lidocaine, ranolazine, nicardipine, quinidine, verapamil;
- hepatitis C medications--boceprevir, telaprevir;
- HIV/AIDS medication--atazanavir, delavirdine, fosamprenavir, efavirenz, darunavir/ritonavir, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir;
- seizure medication--carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, primidone; or
- stomach acid reducers--dexlansoprazole, esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole.
This list is not complete and many other drugs can interact with bosutinib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about bosutinib.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional Bosulif Information
- Bosulif Drug Interactions Center: bosutinib oral
- Bosulif Side Effects Center
- Bosulif FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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