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The amount of fluid (water) retained by the body is controlled primarily by the kidneys. This occurs due to the kidney's ability to control the retention and elimination of sodium and chloride, because the amounts of sodium, chloride, and water in the body are carefully balanced. Thus, if sodium and chloride are eliminated from the body, water also is eliminated. Conversely, if sodium and chloride are retained by the body, so is water.
The elimination of sodium, chloride, and water from the body is somewhat complex. In the kidneys, sodium, chloride, and other small molecules are filtered out of the blood and into the tubules of the kidney where urine is formed. Most of the sodium, chloride, and water are reabsorbed into the blood before the filtered fluid leaves the kidney in the form of urine. To make matters even more complex, there are different mechanisms that are active in different parts of the tu...
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Medical Editor: John P. Cunha, DO, FACOEP
Bumex (bumetanide) is used to treat fluid retention (edema) in people with high blood pressure, congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome. It is a loop diuretic (water pill) that prevents the body from absorbing too much salt, allowing the salt to instead be passed in the urine. This drug is available in generic form. Common side effects include dizziness as your body adjusts to the medication. Tell your doctor if you experience muscle cramps, weakness, tiredness, confusion, dizziness, fainting, drowsiness, dry mouth/thirst, nausea, vomiting, fast/irregular heartbeat, or an unusual decrease in the amount of urine as these may be signs of severe dehydration.
The usual daily dosage of Bumex is 0.5 mg to 2 mg and in most patients is given as a single dose. Products that may interact with this drug include indomethacin, lithium, probenecid, and other drugs that can affect your hearing (including aminoglycoside antibiotics such as gentamicin, tobramycin). If you have diabetes, Bumex may affect your blood sugar level. Bumex may also reduce the potassium level in your blood. During pregnancy, this drug should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
Our Bumex Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Bumex (bumetanide) is indicated for the treatment of edema associated with congestive heart failure, hepatic and renal disease, including the nephrotic syndrome.
Almost equal diuretic response occurs after oral and parenteral administration of bumetanide. Therefore, if impaired gastrointestinal absorption is suspected or oral administration is not practical, bumetanide should be given by the intramuscular or intravenous route.
Successful treatment with Bumex (bumetanide) following instances of allergic reactions to furosemide suggests a lack of cross-sensitivity.
Read the complete drug monograph for Bumex »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using bumetanide and call your doctor at once if you have any of these serious side effects:
Less serious side effects may include:...
Read the complete patient information for Bumex »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Us...
Read the complete consumer information for Bumex »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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