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Buphenyl

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Buphenyl

BUPHENYL®
(sodium phenylbutyrate) Tablets

BUPHENYL®
(sodium phenylbutyrate) Powder

Buphenyl

DRUG DESCRIPTION

BUPHENYL® (sodium phenylbutyrate) Tablets for oral administration and BUPHENYL® (sodium phenylbutyrate) Powder for oral, nasogastric, or gastrostomy tube administration contain sodium phenylbutyrate. Sodium phenylbutyrate is an off-white crystalline substance which is soluble in water and has a strong salty taste. Sodium phenylbutyrate also is freely soluble in methanol and practically insoluble in acetone and diethyl ether. It is known chemically as 4-phenylbutyric acid, sodium salt with a molecular weight of 186 and the molecular formula C10H11O2Na.

Chemical Structure:

BUPHENYL®
  (sodium phenylbutyrate) Structural Formula Illustration

Each tablet of BUPHENYL contains 500 mg of sodium phenylbutyrate and the inactive ingredients microcrystalline cellulose NF, magnesium stearate NF, and colloidal silicon dioxide NF.

Each gram of BUPHENYL Powder contains 0.94 grams of sodium phenylbutyrate and the inactive ingredients calcium stearate NF, and colloidal silicon dioxide NF.

What are the possible side effects of sodium phenylbutyrate (Buphenyl)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using sodium phenylbutyrate and call your doctor at once if you have any of these serious side effects:

Call your doctor at once if you have a serious side effect such as:

  • fast, slow, or uneven heart rate;
  • swelling, rapid weight gain;
  • feeling like you might pass out; or
  • changes in mood, personality, or behavior.

Less serious side effects may...

Read All Potential Side Effects and See Pictures of Buphenyl »

What are the precautions when taking sodium phenylbutyrate tablets (Buphenyl)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain heart problem (congestive heart failure), kidney disease, liver disease, swelling (edema).

This medication contains salt (sodium). Before taking this medication, tell your doctor or pharmacist if you are on a low-salt diet.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit...

Read All Potential Precautions of Buphenyl »

Last reviewed on RxList: 4/22/2009
This monograph has been modified to include the generic and brand name in many instances.

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Buphenyl - User Reviews

Buphenyl User Reviews

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Here is a collection of user reviews for the medication Buphenyl sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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