"Repeated subcutaneous injections of botulinum toxin A (Botox, Allergan) provides analgesic relief to patients with neuropathic pain, a new randomized controlled trial has shown.
The study showed that two series of injections "...
(buprenorphine hydrochloride) Injectable
Proprietary name: Buprenex
Established name: buprenorphine HCI
Route of administration: INTRAVENOUS (C38276), INTRAMUSCULAR (C28161)
Active ingredients (moiety): buprenorphine HCI (buprenorphine)
|1||0.324 : 1||INJECTION, SOLUTION ( C42945)||anhydrous dextrose, water for injection, hydrochloric acid|
Buprenex (buprenorphine hydrochloride) is a narcotic under the Controlled Substances Act due to its chemical derivation from thebaine. Chemically, it is 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4, 5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6, 14- ethenomorphinan-7-methanol, hydrochloride [5α, 7α(S)]. Buprenorphine hydrochloride is a white powder, weakly acidic and with limited solubility in water. Buprenex (buprenorphine) is a clear, sterile, injectable agonist-antagonist analgesic intended for intravenous or intramuscular administration. Each ml of Buprenex contains 0.324 mg buprenorphine hydrochloride (equivalent to 0.3 mg buprenorphine), 50 mg anhydrous dextrose, water for injection and HCI to adjust pH. Buprenorphine hydrochloride has the molecular formula, C29H41NO4HCI, and the following structure:
What are the possible side effects of buprenorphine injection (Buprenex)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Like other narcotic medicines, buprenorphine can slow your breathing. Death may occur if breathing becomes too weak.
Call your doctor at once if you have a serious side effect such as:
- weak or shallow breathing, feeling light-headed, fainting;
- blue lips or fingernails;
- confusion, feelings of extreme happiness;
- fast or slow heart rate; or
- urinating less...
Last reviewed on RxList: 4/22/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Buprenex Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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