"Nov. 2, 2012 -- Safety steps taken in the wake of the fungal meningitis outbreak have worsened drug shortages, raising questions about whether the U.S. must choose between the safety and the availability of crucial medicines.
- Clinician Information:
Buprenex Patient Information including How Should I Take
In this Article
- What is buprenorphine injection (Buprenex)?
- What are the possible side effects of buprenorphine injection (Buprenex)?
- What is the most important information I should know about buprenorphine (Buprenex)?
- What should I discuss with my healthcare provider before using buprenorphine (Buprenex)?
- How should I use buprenorphine (Buprenex)?
- What happens if I miss a dose (Buprenex)?
- What happens if I overdose (Buprenex)?
- What should I avoid while using buprenorphine (Buprenex)?
- What other drugs will affect buprenorphine injection (Buprenex)?
- Where can I get more information?
What should I discuss with my healthcare provider before using buprenorphine (Buprenex)?
You should not use this medication if you are allergic to buprenorphine.
To make sure you can safely use buprenorphine, tell your doctor if you have any of these other conditions:
- asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorders;
- liver or kidney disease;
- a thyroid disorder;
- enlarged prostate, urination problems;
- gallbladder disease;
- curvature of the spine;
- Addison's disease (adrenal gland disorder);
- a history of mental illness, personality disorder, or psychotic episode;
- a history of drug or alcohol addiction; or
- a history of seizures, head injury, or brain tumor.
Buprenorphine may be habit forming and should be used only by the person it was prescribed for. Never share buprenorphine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
FDA pregnancy category C. It is not known whether buprenorphine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using buprenorphine.
Buprenorphine can pass into breast milk and may harm a nursing baby. Do not breast-feed while you are using buprenorphine.
How should I use buprenorphine (Buprenex)?
Buprenorphine is injected into a muscle or into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, syringes, IV tubing, and other items used to inject the medicine.
Buprenorphine is usually given at evenly spaced intervals, up to 6 hours apart. Tell your doctor if buprenorphine does not relieve your pain within 1 hour after an injection.
Prepare your dose in a syringe or IV only when you are ready to give yourself an injection. Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription. Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
If you need surgery, tell the surgeon ahead of time that you are using buprenorphine. You may need to stop using the medicine for a short time.
Do not stop using buprenorphine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using buprenorphine.
Wear a medical alert tag or carry an ID card stating that you use buprenorphine. Any medical care provider who treats you should know that you are using buprenorphine. Make sure your family members know you are using buprenorphine in case they need to speak for you during an emergency.
Store at room temperature away from moisture, heat, and light. Keep track of the amount of medicine used from each new ampule. Buprenorphine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Additional Buprenex Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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