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Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anti-diabetic drugs (e.g., sulfonylureas such as glipizide, glyburide, chlorpropamide), birth control pills (see also How To Use section), oral antibiotics, warfarin.

Beta-blocker medications (e.g., metoprolol, propranolol, glaucoma eye drops such as timolol) may prevent the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). Other symptoms of low blood sugar such as dizziness, hunger, or sweating are unaffected by these drugs.

While exenatide does not cause low blood sugar (hypoglycemia) itself, it may increase the risk of low blood sugar when used in combination with certain other diabetes medications (pioglitazone, rosiglitazone, sulfonylureas such as chlorpropamide, glipizide, glyburide).

Be sure you are aware of the signs of low blood sugar and how to prevent and treat it (see your other diabetes medication leaflet for more details). Talk with you doctor or pharmacist about whether your dose of sulfonylurea needs to be lowered or not.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe nausea, severe vomiting and rapidly dropping blood sugar levels (hypoglycemia), resulting in confusion, fainting, sweating, fast heartbeat.

NOTES: Do not share this medication, the pens or the needles with others.

You should attend a diabetes education program to understand diabetes, its complications, and all the important aspects of its treatment including meals/diet, exercise, personal hygiene, medications and getting regular eye, foot and medical exams.

Keep all medical appointments. Laboratory and/or medical tests (e.g., kidney function tests, fasting blood glucose, hemoglobin A1c) should be performed periodically to monitor for side effects and response to therapy. Check your blood sugar levels regularly as directed by your doctor or pharmacist.

MISSED DOSE: If a dose is missed, skip the missed dose and resume your usual dosing schedule with the next scheduled dose. Do not double the dose to catch up.

STORAGE: Before using the exenatide pen for the first time, store it in the refrigerator at 36-46 degrees F (2-8 degrees C). Do not freeze. After first use, exenatide can be stored at room temperature at or below 77 degrees F (25 degrees C). Protect from light at all times. Discard 30 days after first use, even if some drug remains in the pen. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).

Information last revised September 2010 Copyright(c) 2010 First DataBank, Inc.