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Cafcit

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Cafcit

CAFCIT®
(caffeine citrate) Injection

CAFCIT®
(caffeine citrate) Oral Solution

Cafcit

DRUG DESCRIPTION

Both CAFCIT® (caffeine citrate) Injection for intravenous administration and CAFCIT® (caffeine citrate) Oral Solution are clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solutions adjusted to pH 4.7. Each mL contains 20 mg caffeine citrate (equivalent to 10 mg of caffeine base) prepared in solution by the addition of 10 mg caffeine anhydrous to 5.0 mg citric acid monohydrate, 8.3 mg sodium citrate dihydrate and Water for Injection.

Caffeine, a central nervous system stimulant, is an odorless white crystalline powder or granule, with a bitter taste. It is sparingly soluble in water and ethanol at room temperature. The chemical name of caffeine is 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione. In the presence of citric acid it forms caffeine citrate salt in solution. The structural formula and molecular weight of caffeine citrate follows.

CAFCIT®
  (caffeine citrate) Structural Formula Illustration

What are the possible side effects of caffeine citrate (Cafcit)?

Get emergency medical help if your child has any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using caffeine citrate and call your doctor at once if your child has any of these serious side effects:

  • stomach pain, tenderness, bloating,
  • constipation or diarrhea;
  • green-colored vomit;
  • blood in the stools;
  • unusual weakness;
  • seizure (convulsions);
  • twitching or uncontrolled muscle movements; or
  • fever, fast or slow heart...

Read All Potential Side Effects and See Pictures of Cafcit »

What are the precautions when taking caffeine citrate (Cafcit)?

Before taking caffeine citrate, tell your doctor or pharmacist if your infant is allergic to it; or if your infant has any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your infant's medical history, especially of: heart disease, kidney disease, liver disease, stomach problems (e.g., peptic ulcers, necrotizing enterocolitis), seizures.

Caution is advised when using this drug in infants because they may be more sensitive to its effects, especially the stimulant effects (e.g., trouble sleeping, restlessness, nervousness).

This medication should be used only when clearly needed during pregnancy....

Read All Potential Precautions of Cafcit »

Last reviewed on RxList: 5/4/2009
This monograph has been modified to include the generic and brand name in many instances.

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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