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Caffeine and Sodium Benzoate

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Caffeine and Sodium Benzoate Injection

OVERDOSE

Acute toxicity involving caffeine has been reported rarely. Mild delirium, insomnia, diuresis, dehydration, fever commonly occur with overdosage. More serious symptoms of overdosage include cardiac arrhythmias and clonic-tonic convulsions. In adults, IV doses of 57 mg/kg of body weight and oral doses of 18.50 grams have been fatal. In one 5-year-old patient, death occurred following oral ingestion of approximately 3 grams caffeine. Convulsions may be treated with IV administration of diazepam or a barbiturate such as pentobarbital sodium.

CONTRAINDICATIONS

None known.

Last reviewed on RxList: 9/30/2008
This monograph has been modified to include the generic and brand name in many instances.

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