"A large-scale genomic analysis found that non-inherited mutations in hundreds of genes together account for about 1 in 10 cases of severe congenital heart defects. The findings bring us closer to understanding the most common type of birth defect"...
(verapamil hydrochloride) Tablets
CALAN (verapamil HCl) is a calcium ion influx inhibitor (slow-channel blocker or calcium ion antagonist) available for oral administration in film-coated tablets containing 40 mg, 80 mg, or 120 mg of verapamil hydrochloride.
The structural formula of verapamil HCl is:
C27H38N2O4 • HCl M.W. = 491.08
Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl] methylamino]propyl]-3,4dimethoxy-α-(1-methylethyl) hydrochloride
Verapamil HCl is an almost white, crystalline powder, practically free of odor, with a bitter taste. It is soluble in water, chloroform, and methanol. Verapamil HCl is not chemically related to other cardioactive drugs.
Inactive ingredients include microcrystalline cellulose, corn starch, gelatin, hydroxypropyl cellulose, hypromellose, iron oxide colorant, lactose, magnesium stearate, polyethylene glycol, talc, and titanium dioxide.
What are the possible side effects of verapamil?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- fast or slow heartbeats;
- feeling like you might pass out;
- fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
- restless muscle movements in your eyes, tongue, jaw, or neck;
- feeling short of breath, even with mild exertion;
- swelling, rapid weight gain; or
- nausea, stomach...
What are the precautions when taking verapamil hcl (Calan)?
Before taking verapamil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain types of heart rhythm problems (such as second- or third-degree atrioventricular block, sick sinus syndrome unless you have a pacemaker, Wolff-Parkinson-White syndrome, Lown-Ganong-Levine syndrome).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, heart failure, certain muscle/nerve...
Last reviewed on RxList: 12/2/2013
This monograph has been modified to include the generic and brand name in many instances.
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