May 27, 2017
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Calcium Disodium Versenate

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Calcium Disodium Versenate

Calcium Disodium Versenate Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 6/1/2016

Calcium Disodium Versenate (edetate calcium disodium) Injection is a chelating agent used to treat lead poisoning. Common side effects of Calcium Disodium Versenate include:

  • fever
  • chills
  • tired feeling
  • muscle or
  • joint pain
  • numbness or tingly feeling
  • tremors
  • runny or stuffy nose
  • sneezing
  • watery eyes
  • mild skin rash
  • headache, or
  • pain where the medicine was injected

Calcium Disodium Versenate is administered intravenously and a physician determines the dosage. Calcium Disodium Versenate may interact with insulin zinc, or steroids. Tell your doctor all medications and supplements you use. Calcium Disodium Versenate is not expected to be harmful to a fetus. Tell your doctor if you are pregnant before receiving this medication. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Our Calcium Disodium Versenate (edetate calcium disodium) Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Calcium Disodium Versenate in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have any of these serious side effects:

  • urinating less than usual or not at all;
  • drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting;
  • swelling, weight gain, feeling short of breath;
  • feeling like you might pass out; or
  • fast, slow, or uneven heart rate.

Less serious side effects include:

  • fever, chills, tired feeling, and muscle or joint pain;
  • numbness or tingly feeling;
  • tremors;
  • runny or stuffy nose, sneezing, water eyes;
  • mild skin rash;
  • headache; or
  • pain where the medicine was injected.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Calcium Disodium Versenate (Edetate Calcium Disodium Injection)

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Calcium Disodium Versenate FDA Prescribing Information: Side Effects
(Adverse Reactions)


The following adverse effects have been associated with the use of edetate calcium disodium:

Body as a Whole: pain at intramuscular injection site, fever, chills, malaise, fatigue, myalgia, arthralgia.

Cardiovascular: hypotension, cardiac rhythm irregularities.

Renal: acute necrosis of proximal tubules (which may result in fatal nephrosis), infrequent changes in distal tubules and glomeruli.

Urinary: glycosuria, proteinuria, microscopic hematuria and large epithelial cells in urinary sediment.

Nervous System: tremors, headache, numbness, tingling.

Gastrointestinal: cheilosis, nausea, vomiting, anorexia, excessive thirst.

Hepatic: mild increases in SGOT and SGPT are common, and return to normal within 48 hours after cessation of therapy.

Immunogenic: histamine-like reactions (sneezing, nasal congestion, lacrimation), rash.

Hematopoietic: transient bone marrow depression, anemia.

Metabolic: zinc deficiency, hypercalcemia.

Read the entire FDA prescribing information for Calcium Disodium Versenate (Edetate Calcium Disodium Injection)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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