Camptosar Injection (Irinotecan Hydrochloride) Drug Overview of Drug Interactions and Missed Dose for Patients and Caregivers at RxList

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May 25, 2012

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Colon cancer facts

Colorectal cancer is a malignant tumor arising from the inner wall of the large intestine.
Colorectal cancer is the third leading cause of cancer in males and fourth in females in the U.S.
Risk factors for colorectal cancer include heredity, colon polyps, and long-standing ulcerative colitis.
Most colorectal cancers develop from polyps. Removal of colon polyps can prevent colorectal cancer.
Colon polyps and early cancer can have no symptoms. Therefore regular screening is important.
Diagnosis of colorectal cancer can be made by barium enema or by colonoscopy with biopsy confirmation of cancer tissue.
Treatment of colorectal cancer depends on the location, size, and extent of cancer spread, as well as the age and health of the patient.
Surgery is the most c...

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Camptosar Injection Consumer (continued)

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: atazanavir, drugs affecting liver enzymes that remove irinotecan from your body (such as rifamycins including rifabutin, certain anti-seizure medicines including carbamazepine/phenytoin/phenobarbital), laxatives, "water pills"/diuretics (e.g., furosemide).

Avoid taking St. John's wort within 2 weeks before or during treatment with this medication, and avoid taking ketoconazole within 1 week before or during treatment with this medication.

Avoid eating foods or taking products containing tumeric (curcumin) while being treated with irinotecan. It may decrease this medication's effects. Consult your doctor or pharmacist for more details.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: signs of infection (e.g., persistent sore throat, fever), severe diarrhea.

NOTES: Laboratory and/or medical tests (e.g., complete blood count, hemoglobin, platelets) should be performed regularly to monitor your progress or check for side effects. Consult your doctor for more details.

MISSED DOSE: For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor to establish a new dosing schedule.

STORAGE: Not applicable. This medication is given in a clinic and will not be stored at home.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).