"NEW YORK (Reuters Health) - Triple therapy combining a proton-pump inhibitor (PPI), amoxicillin, and high-dose metronidazole (PAM) given thrice daily for 14 days provides Helicobacter pylori eradication rates similar to those with triple-therapy "...
CANASA is indicated in adults for the treatment of mildly to moderately active ulcerative proctitis.
DOSAGE AND ADMINISTRATION
The recommended dosage of CANASA in adults is 1000 mg administered rectally once daily at bedtime for 3 to 6 weeks depending on symptoms and sigmoidoscopic findings. Safety and effectiveness of CANASA beyond 6 weeks have not been established.
- Evaluate renal function prior to initiation of CANASA therapy and periodically while on therapy.
- Do not cut or break the suppository.
- Retain the suppository for one to three hours or longer, if possible.
- If a dose of CANASA is missed, administer as soon as possible, unless it is almost time for next dose. Do not use two CANASA suppositories at the same time to make up for a missed dose.
- CANASA suppositories will cause staining of direct contact surfaces, including but not limited to fabrics, flooring, painted surfaces, marble, granite, vinyl, and enamel. Keep CANASA away from these surfaces to prevent staining.
Dosage Forms And Strengths
CANASA Suppository: 1000 mg mesalamine in a bullet shaped, light tan to grey suppository.
Storage And Handling
CANASA 1000 mg suppositories for rectal administration are available as bullet shaped, light tan to grey suppositories containing 1000 mg mesalamine supplied in boxes of 30 and 42 individually plastic wrapped suppositories (NDC 58914-501-56 and 58914-50142).
Store below 25°C (77°F), may be refrigerated. Keep away from direct heat, light or humidity.
Distributed by: Allergan USA, Inc. Irvine, CA 92612. Revised: Sep 2016This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 12/16/2016
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