"Make sure your child gets all doses of Hib vaccine for best protection against Hib disease. Hib bacteria can cause serious diseases like meningitis (an infection of the fluid and lining around the brain and spinal cord).
How Can I Prot"...
In 6 healthy subjects who received a single 210-mg dose, no significant adverse reactions were reported. Multiple doses above 150 mg daily have not been studied. Caspofungin is not dialyzable. The minimum lethal dose of caspofungin in rats was 50 mg/kg, a dose which is equivalent to 10 times the recommended daily dose based on relative body surface area comparison.
In clinical trials, one pediatric patient (16 years of age) unintentionally received a single dose of caspofungin of 113 mg (on Day 1), followed by 80 mg daily for an additional 7 days. No clinically significant adverse reactions were reported.
Last reviewed on RxList: 8/12/2013
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