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Cancidas

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Cancidas

Cancidas

OVERDOSE

In 6 healthy subjects who received a single 210-mg dose, no significant adverse reactions were reported. Multiple doses above 150 mg daily have not been studied. Caspofungin is not dialyzable. The minimum lethal dose of caspofungin in rats was 50 mg/kg, a dose which is equivalent to 10 times the recommended daily dose based on relative body surface area comparison.

In clinical trials, one pediatric patient (16 years of age) unintentionally received a single dose of caspofungin of 113 mg (on Day 1), followed by 80 mg daily for an additional 7 days. No clinically significant adverse reactions were reported.

CONTRAINDICATIONS

CANCIDAS is contraindicated in patients with hypersensitivity (e.g., anaphylaxis) to any component of this product [see ADVERSE REACTIONS].

Last reviewed on RxList: 8/12/2013
This monograph has been modified to include the generic and brand name in many instances.

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