Cancidas
Fungal Meningitis Patients: A Long Road to Recovery »
"Dec. 26, 2012 -- Johnnie McKee thought she was out of the woods.
McKee, a 72-year-old grandmother of four from Bethpage, Tenn., was one of nearly 14,000 people who found out this fall that they'd been exposed to tainted medications made by "...
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Cancidas
OVERDOSE
In 6 healthy subjects who received a single 210-mg dose, no significant adverse reactions were reported. Multiple doses above 150 mg daily have not been studied. Caspofungin is not dialyzable. The minimum lethal dose of caspofungin in rats was 50 mg/kg, a dose which is equivalent to 10 times the recommended daily dose based on relative body surface area comparison.
In clinical trials, one pediatric patient (16 years of age) unintentionally received a single dose of caspofungin of 113 mg (on Day 1), followed by 80 mg daily for an additional 7 days. No clinically significant adverse reactions were reported.
CONTRAINDICATIONS
CANCIDAS is contraindicated in patients with hypersensitivity (e.g., anaphylaxis) to any component of this product [see ADVERSE REACTIONS].
Last reviewed on RxList: 1/30/2013
This monograph has been modified to include the generic and brand name in many instances.
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