"The U.S. Food and Drug Administration today allowed marketing of the Eclipse System for the treatment of fecal incontinence (FI) in adult women.
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(mepenzolate bromide USP)
CANTIL tablets for oral administration contain 25 mg mepenzolate bromide USP. The anticholinergic agent mepenzolate bromide USP chemically is 3-[(hydroxydiphenylacetyl)oxy]-1,1-dimethylpiperidinium bromide and has the following structure:
Mepenzolate bromide occurs as a white or light cream-colored powder, which is freely soluble in methanol, slightly soluble in water and chloroform, and practically insoluble in ether. Each yellow tablet contains 25 mg mepenzolate bromide USP. This tablet also contains inactive ingredients: confectioners' sugar, corn starch, corn syrup solids, FD&C Yellow No. 5 (tartrazine), (see PRECAUTIONS, General), lactose, magnesium stearate and microcrystalline cellulose.
What are the possible side effects of mepenzolate (Cantil)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using mepenzolate and call your doctor at once if you have any of these serious side effects:
- urinating less than usual or not at all;
- confusion, hallucinations;
- unusual thoughts or behavior; or
- fast, pounding, or uneven heartbeats.
Less serious side effects may include:
- drowsiness, dizziness, headache;
- blurred vision;
What are the precautions when taking mepenzolate bromide (Cantil)?
Before taking mepenzolate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: glaucoma, myasthenia gravis, movement/blockage disorders of the stomach/bowels (e.g., paralytic ileus, pyloroduodenal stenosis, achalasia, intestinal atony), difficulty urinating (e.g., prostatic hypertrophy), a certain bowel disorder (toxic megacolon).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease,...
Last reviewed on RxList: 5/6/2009
This monograph has been modified to include the generic and brand name in many instances.
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