Cantil
Is a New Crohn's Disease Treatment on the Horizon? »
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In the new study, some people with moderate to severe Crohn's given Stelara (ustekinumab) began to see imp"...
Read the Is a New Crohn's Disease Treatment on the Horizon? article »
Cantil
CLINICAL PHARMACOLOGY
CANTIL (mepenzolate bromide) diminishes gastric acid and pepsin secretion. CANTIL (mepenzolate bromide) also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. Radiotracer studies in which CANTIL (mepenzolate bromide) -14C was used in animals and humans indicate the absorption following oral administration, as with other quaternary ammonium compounds, is low. Between 3 and 22% of an orally administered dose is excreted in the urine over a 5-day period, with the majority of the radioactivity appearing on Day 1. The remainder appears in the next 5 days in the feces and presumably has not been absorbed.
Last reviewed on RxList: 5/6/2009
This monograph has been modified to include the generic and brand name in many instances.
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