"The U.S. Food and Drug Administration today allowed marketing of the Eclipse System for the treatment of fecal incontinence (FI) in adult women.
Fecal incontinence is the inability to control bowel movements and is a common problem, espec"...
CANTIL (mepenzolate bromide) diminishes gastric acid and pepsin secretion. CANTIL (mepenzolate bromide) also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. Radiotracer studies in which CANTIL (mepenzolate bromide) -14C was used in animals and humans indicate the absorption following oral administration, as with other quaternary ammonium compounds, is low. Between 3 and 22% of an orally administered dose is excreted in the urine over a 5-day period, with the majority of the radioactivity appearing on Day 1. The remainder appears in the next 5 days in the feces and presumably has not been absorbed.
Last reviewed on RxList: 5/6/2009
This monograph has been modified to include the generic and brand name in many instances.
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