"The U.S. Food and Drug Administration today approved Movantik (naloxegol), an oral treatment for opioid-induced constipation in adults with chronic non-cancer pain.
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DOSAGE AND ADMINISTRATION
The usual adult dose is 1 or 2 tablets (25 or 50 mg) 4 times a day preferably with meals and at bedtime. Begin with the lower dosage when possible and adjust subsequently according to the patient's response.
Safety and efficacy in pediatric patients have not been established.
In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. (See PRECAUTIONS, Geriatric Use.)
25 mg mepenzolate bromide, compressed yellow tablets debossed MERRELL 37.
NDC 0068-0037-01: bottles of 100
Keep tightly closed. Store at room temperature, preferably below 86°F. Protect from excessive heat. Dispense in tight containers with child-resistant closure.
Rev. February 2006. Manufactured for: sanofi-aventis U.S. LLC Bridgewater, NJ 08807.
Last reviewed on RxList: 5/6/2009
This monograph has been modified to include the generic and brand name in many instances.
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