Carbocaine
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Carbocaine
Carbocaine™
(mepivacaine hydrochloride) Injection, USP
These solutions are not intended for spinal anesthesia or dental use
DRUG DESCRIPTION
Mepivacaine hydrochloride is 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl, monohydrochloride and has the following structural formula:
 |
C15H22N2O HCI
It is a white crystalline odorless powder, soluble in water, but very resistant to both acid and alkaline hydrolysis.
CARBOCAINE (mepivacaine) is a local anesthetic available as sterile isotonic solutions (clear, colorless) in concentrations of 1%, 1.5%, and 2% for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks.
Mepivacaine hydrochloride is related chemically and pharmacologically to the amide-type local anesthetics. It contains an amide linkage between the aromatic nucleus and the amino group.
Composition of Available Solutions*
| 1% Single- Dose 30 mL Vial mg/mL |
1% Multiple- Dose 50 mL Vial mg/mL |
1.5% Single- Dose 30 mL Vial mg/mL |
2% Single- Dose 20 mL Vial mg/mL |
2% Multiple- Dose 50 mL Vial mg/mL |
|
| Mepivacaine hydrochloride | 10 | 10 | 15 | 20 | 20 |
| Sodium chloride | 6.6 | 7 | 5.6 | 4.6 | 5 |
| Potassium chloride | 0.3 | 0.3 | 0.3 | ||
| Calcium chloride | 0.33 | 0.33 | 0.33 | ||
| Methylparaben | 1 | 1 | |||
| *In Water for Injection. | |||||
The pH of the solution is adjusted between 4.5 and 6.8 with sodium hydroxide or hydrochloric acid.
Last reviewed on RxList: 3/4/2010
This monograph has been modified to include the generic and brand name in many instances.
Additional Carbocaine Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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