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Cardene

What are calcium channel blockers (CCBs) and how do they work?

Calcium channel blockers are drugs that block the entry of calcium into the muscle cells of the heart and arteries.

  • The entry of calcium is critical for the conduction of the electrical signal that passes from muscle cell to muscle cell of the heart, and signals the cells to contract.
  • It also is necessary in order for the muscle cells to contract and thereby pump blood.
  • In the arteries, the entry of calcium into muscle cells causes contraction of the cells and thereby dilates (widens) the arteries.
  • Thus, by blocking the entry of calcium, calcium channel blockers reduce electrical conduction within the heart, decrease the force of contraction (work) of the muscle cells, and dilate arteries.
  • Dilation of the arteries reduces blood pressure and thereby the effort the heart must exert to pump blood.
  • Combined with decr...

Cardene SR

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Cardene Drug Center

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Cardene Prescribing Information: Indications & Dosage

 CARDENE® SR (nicardipine hydrochloride) Structural Formula Illustration

CARDENE SR (nicardipine hydrochloride sustained release capsules) is indicated for the treatment of hypertension. CARDENE SR may be used alone or in combination with other antihypertensive drugs.

Read the complete drug monograph for Cardene »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Cardene Patient Information: Side Effects

If you experience any of the following serious side effects, stop taking nicardipine and contact your doctor immediately or seek emergency medical treatment:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • unusually fast or slow heartbeats;
  • fainting or severe dizziness;
  • abnormal behavior or psychosis;
  • chest pain or worsening angina;
  • jaundice (yellowing of the skin or eyes); or
  • swelling of the legs or ankles.

Other, less...

Read the complete patient information for Cardene »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Cardene Consumer Information: Uses

Nicardipine is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Nicardipine is called a calcium channel blocker. It works by relaxing blood vessels so blood can flow more easily.

Nicardipine is also used to prevent certain types of chest pain (angina). It may help to increase your ability to exercise and decrease the frequency of angina attacks. This medication must be taken regularly to be effective. It should not be used to treat attacks of chest pain when they occur....

Read the complete consumer information for Cardene »

What is Cardene Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Hypertension

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