Cardizem CD (Diltiazem HCl) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Cardizem CD

Angina »

Angina facts

Angina is one of many causes of chest pain.
Angina is chest pain that is a result of inadequate oxygen supply to the heart muscle.
Angina can be caused by coronary artery disease or spasm of the coronary arteries.
Electrocardiogram (ECG or EKG), exercise stress test, stress echocardiography, stress thallium, and cardiac catheterization are important in the diagnosis of angina.
Treatment of angina includes rest, medications, angioplasty, and/or coronary artery bypass surgery.

Introduction to angina

Angina is one of the serious causes of chest pain. “Angina” is an abbreviation of angina pectoris, a Latin term for “squeezing of the chest.” Chest pain is a common symptom caused by many different conditions. Some causes require prompt medical attention, such as angina, heart attack, blood clots i...

Read the Angina article »

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Cardizem CD

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CARDIZEM® CD
(diltiazem HCl) Capsules

DRUG DESCRIPTION

Cardizem (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2, 3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride,(+)-cis-. The chemical structure is:

CARDIZEM® CD (diltiazem HCl) Structural Formula Illustration

Diltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste. It is soluble in water, methanol, and chloroform. It has a molecular weight of 450.98. Cardizem CD (diltiazem hcl) is formulated as a once-a-day extended-release capsule containing 120 mg, 180 mg, 240 mg, 300 mg, or 360 mg diltiazem hydrochloride. The 120 mg, 180 mg, 240 mg, and 300 mg capsules also contain: acetyl tributyl citrate, ammonio methacrylate copolymer dispersion, black iron oxide (300 mg), castor oil, ethylcellulose, FD&C Blue #1, fumaric acid, gelatin, silicon dioxide, simethicone, starch, stearic acid, sucrose, talc, titanium dioxide and white wax. The 360 mg capsule also contains: acetyl tributyl citrate, ammonio methacrylate copolymer dispersion, diethyl phthalate, FD&C Blue #1, gelatin, povidone, simethicone, sodium lauryl sulfate, starch, sucrose, talc and titanium dioxide.

For oral administration.

What are the precautions when taking diltiazem hcl (Cardizem CD)?

Before taking diltiazem, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain types of heart rhythm problems (such as sick sinus syndrome/atrioventricular block unless you have a pacemaker).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, heart failure.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires...

Read All Potential Precautions of Cardizem CD »

Last reviewed on RxList: 1/5/2011
This monograph has been modified to include the generic and brand name in many instances.