Cardizem LA (Diltiazem) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Cardizem LA

Angina »

Angina facts

Angina is one of many causes of chest pain.
Angina is chest pain that is a result of inadequate oxygen supply to the heart muscle.
Angina can be caused by coronary artery disease or spasm of the coronary arteries.
Electrocardiogram (ECG or EKG), exercise stress test, stress echocardiography, stress thallium, and cardiac catheterization are important in the diagnosis of angina.
Treatment of angina includes rest, medications, angioplasty, and/or coronary artery bypass surgery.

Introduction to angina

Angina is one of the serious causes of chest pain. â€œAnginaâ€ is an abbreviation of angina pectoris, a Latin term for â€œsqueezing of the chest.â€ Chest pain is a common symptom caused by many different conditions. Some causes require prompt medical attention, such as angina, heart attack, blood clots i...

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Cardizem LA

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CARDIZEM® LA
(diltiazem hydrochloride) Extended-Release Tablets

DRUG DESCRIPTION

Cardizem LA (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)-one, 3(acetyloxy)-5-[2-(dimethylamino)ethyl]-2, 3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride,(+)-cis-. The chemical structure is:

CARDIZEM® LA (diltiazem Hydrochloride) Structural Formula Illustration

Diltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste. It is soluble in water, methanol, and chloroform. It has a molecular weight of 450.99. Cardizem LA (diltiazem) Tablets, for oral administration are formulated as a once-a-day extended-release tablet containing 120 mg, 180 mg, 240 mg, 300 mg, or 360 mg diltiazem hydrochloride.

Also contains: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, ethyl acrylate and methyl methacrylate copolymer dispersion, hydrogenated vegetable oil, hypromellose, magnesium stearate, microcrystalline cellulose, microcrystalline wax, polydextrose, polyethylene glycol, polysorbate, povidone, pregelatinized starch, simethicone, sodium starch glycolate, sucrose stearate, talc, and titanium dioxide.

What are the possible side effects of diltiazem?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

fast or slow heartbeats;
feeling light-headed, fainting;
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
feeling short of breath, even with mild exertion;
swelling, rapid weight gain; or
nausea, stomach pain, low...

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What are the precautions when taking diltiazem (Cardizem LA)?

Before taking diltiazem, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain types of heart rhythm problems (such as sick sinus syndrome/atrioventricular block unless you have a pacemaker).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, heart failure, narrowing of any part of the stomach/intestines.

This drug may make you dizzy. Do not drive, use...

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Last reviewed on RxList: 1/5/2011
This monograph has been modified to include the generic and brand name in many instances.