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Cardizem LA

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Cardizem LA

CARDIZEM® LA
(diltiazem hydrochloride) Extended-Release Tablets

Cardizem LA

DRUG DESCRIPTION

Cardizem LA (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker or calcium antagonist). Chemically, diltiazem hydrochloride is 1,5-Benzothiazepin-4(5H)-one, 3(acetyloxy)-5-[2-(dimethylamino)ethyl]-2, 3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride,(+)-cis-. The chemical structure is:

CARDIZEM® LA (diltiazem Hydrochloride) Structural Formula Illustration

Diltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste. It is soluble in water, methanol, and chloroform. It has a molecular weight of 450.99. Cardizem LA (diltiazem) Tablets, for oral administration are formulated as a once-a-day extended-release tablet containing 120 mg, 180 mg, 240 mg, 300 mg, or 360 mg diltiazem hydrochloride.

Also contains: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, ethyl acrylate and methyl methacrylate copolymer dispersion, hydrogenated vegetable oil, hypromellose, magnesium stearate, microcrystalline cellulose, microcrystalline wax, polydextrose, polyethylene glycol, polysorbate, povidone, pregelatinized starch, simethicone, sodium starch glycolate, sucrose stearate, talc, and titanium dioxide.

What are the possible side effects of diltiazem?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • a red, blistering skin rash;
  • swelling in your hands or feet;
  • trouble breathing;
  • slow heartbeats;
  • dizziness, fainting, fast or pounding heartbeat;
  • upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • severe skin reaction -- fever, sore...

Read All Potential Side Effects and See Pictures of Cardizem LA »

What are the precautions when taking diltiazem (Cardizem LA)?

Before taking diltiazem, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain types of heart rhythm problems (such as sick sinus syndrome/atrioventricular block unless you have a pacemaker).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, heart failure, narrowing of any part of the stomach/intestines.

This drug may make you dizzy. Do not drive, use...

Read All Potential Precautions of Cardizem LA »

Last reviewed on RxList: 1/5/2011
This monograph has been modified to include the generic and brand name in many instances.

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Cardizem LA - User Reviews

Cardizem LA User Reviews

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Here is a collection of user reviews for the medication Cardizem LA sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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