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This drug should not be used with the following medications because very serious interactions may occur: cidofovir, ketorolac, mifepristone, flu vaccine given in the nose.

If you are currently using any of these medications listed above or received the flu vaccine in the last month, tell your doctor or pharmacist before starting this medication.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anti-platelet drugs (e.g., clopidogrel), "blood thinners" (e.g., heparin, warfarin), bisphosphonates taken by mouth (e.g., alendronate), carbonic anhydrase inhibitors (e.g., acetazolamide), corticosteroids (e.g., prednisone), cyclosporine, drugs for diabetes (e.g., insulin, sulfonylureas such as glipizide), drugs for gout (e.g., probenecid, sulfinpyrazone), drugs for high blood pressure (e.g., ACE inhibitors such as captopril/lisinopril, angiotensin II receptor blockers such as as losartan, and beta blockers such as metoprolol), drugs that change the acidity of urine (e.g., antacids, citrates, sodium bicarbonate, high doses of vitamin C/ascorbic acid), lithium, methotrexate, NSAIDs and other salicylates (e.g., ibuprofen, naproxen, salsalate), pemetrexed, SSRI antidepressants (e.g., fluoxetine, paroxetine), "water pills" (diuretics such as furosemide, hydrochlorothiazide).

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness. Alcoholic beverages will also increase the drowsiness effect. Ask your pharmacist about using those products safely.

Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (NSAIDs such as ibuprofen, naproxen, or aspirin) that are similar to the aspirin in this product. Low-dose aspirin should be continued if prescribed by your doctor for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day). Consult your doctor or pharmacist for more details.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms may include: ringing in ears, confusion, fast/irregular heartbeat, seizures, loss of consciousness.

NOTES: Do not share this medication with others.

This medication has been prescribed for your current condition only. Do not use it later for another condition unless told to do so by your doctor. A different medication may be necessary in that case.

Laboratory and/or medical tests (e.g., complete blood count, kidney/liver tests) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised May 2010 Copyright(c) 2010 First DataBank, Inc.