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DOSAGE AND ADMINISTRATION
The dose of Catapres® (clonidine hydrochloride, USP) tablets must be adjusted according to the patient's individual blood pressure response. The following is a general guide to its administration.
0.1 mg tablet twice daily (morning and bedtime). Elderly patients may benefit from a lower initial dose.
Further increments of 0.1 mg per day may be made at weekly intervals if necessary until the desired response is achieved. Taking the larger portion of the oral daily dose at bedtime may minimize transient adjustment effects of dry mouth and drowsiness. The therapeutic doses most commonly employed have ranged from 0.2 mg to 0.6 mg per day given in divided doses. Studies have indicated that 2.4 mg is the maximum effective daily dose, but doses as high as this have rarely been employed.
Patients with renal impairment may benefit from a lower initial dose. Patients should be carefully monitored. Since only a minimal amount of clonidine is removed during routine hemodialysis, there is no need to give supplemental clonidine following dialysis.
Catapres® (clonidine hydrochloride, USP) tablets are supplied as follows:
|Dose (mg)||Color||Marking||Bottle of 100|
|0.1||Tan||BI 6||NDC 0597-0006-01|
|0.2||Orange||BI 7||NDC 0597-0007-01|
|0.3||Peach||BI 11||NDC 0597-0011-01|
Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F) [see USP Controlled Room Temperature].
Dispense in tight, light-resistant container.
Distributed by: Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877 USA. Manufactured by: Boehringer Ingelheim Promeco S.A. de C.V., Mexico City, Mexico. Licensed from: Boehringer Ingelheim, International GmbH,Address medical inquiries to: (800) 542-6257 or (800) 459-9906. Revised: May 2012This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 8/19/2015
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