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Cefadroxil

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Cefadroxil

Cefadroxil

Cefadroxil Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Cefadroxil (cefadroxil hemihydrate) is a cephalosporin antibiotic used to treat infections of the urinary tract, skin and soft-tissue, throat, and tonsils caused by bacteria that are susceptible to its effects. It also is used for prevention of infection of the inner layer of the heart (endocarditis) due to surgical procedures. This medication is available in generic form. Common side effects include diarrhea, nausea, abdominal pain, vomiting, and rash.

The recommended adult dose of Cefadroxil depends on the infection being treated, and varies from 1 to 2 grams, taken once daily or in two divided doses. Pediatric dose is based on the child's weight. Cefadroxil may interact with some vaccines, reducing their effectiveness. Tell your doctor all medications and supplements you use and all vaccines you recently received. During pregnancy, Cefadroxil should be used only if prescribed. Cefadroxil passes into breast milk. Consult your doctor before breastfeeding.

Our Cefadroxil (cefadroxil hemihydrate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Cefadroxil FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Gastrointestinal

Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment (see WARNINGS). Dyspepsia, nausea and vomiting have been reported rarely. Diarrhea has also occurred.

Hypersensitivity

Allergies (in the form of rash, urticaria, angioedema, and pruritus) have been observed. These reactions usually subsided upon discontinuation of the drug. Anaphylaxis has also been reported.

Other

Other reactions have included hepatic dysfunction including cholestasis and elevations in serum transaminase, genital pruritus, genital moniliasis, vaginitis, moderate transient neutropenia, fever. Agranulocytosis, thrombocytopenia,idiosyncratic hepatic failure, erythema multiforme, Stevens-Johnson syndrome, serum sickness, and arthralgia have been rarely reported.

In addition to the adverse reactions listed above which have been observed in patients treated with cefadroxil (cefadroxil (cefadroxil hemihydrate) hemihydrate) , the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics:

Toxic epidermal necrolysis, abdominal pain, superinfection, renal dysfunction, toxic nephropathy, hepatic dysfunction including cholestasis, aplastic anemia, hemolytic anemia, hemorrhage, prolonged prothrombin time, positive Coombs’ test, increased BUN, increased creatinine, elevated alkaline phosphatase, elevated aspartate aminotransferase (AST), elevated alanine aminotransferase (ALT), elevated bilirubin, elevated LDH, eosinophilia, pancytopenia, neutropenia.

Several cephalosporins have been implicated in triggering seizures, particularly in patients with renal impairment, when the dosage was not reduced (see DOSAGE AND ADMINISTRATION and OVERDOSAGE). If seizures associated with drug therapy occur, the drug should be discontinued. Anticonvulsant therapy can be given if clinically indicated.

Read the entire FDA prescribing information for Cefadroxil (Cefadroxil Hemihydrate) »

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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