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Cefazolin Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Cefazolin and dextrose for injection is an antibiotic used to treat many different kinds of bacterial infections. Common side effects of Cefazolin and dextrose for injection include:
- injection site reactions (pain, swelling, skin rash, or a hard lump),
- stomach pain,
- stomach cramps,
- loss of appetite,
- skin rash or itching,
- white patches or sores inside the mouth or on the lips,
- vaginal itching or discharge,
- rectal itching,
- headache, and
- allergic reactions.
The dose of cefazolin varies depending on the condition being treated and its severity. For mild infections, the recommended adult dose is 250 mg to 500 mg every 8 hours. For more severe infections the dose is 500 mg to 1 g every 6 to 8 hours. Cefazolin may interact with probenecid. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant before receiving this medication. Cefazolin passes into breast milk in very low concentrations. Consult your doctor before breastfeeding.
Our cefazolin and dextrose for injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Cefazolin FDA Prescribing Information: Side Effects
The following serious adverse reactions to cefazolin are described below and elsewhere in the labeling:
- Hypersensitivity reactions [see WARNINGS AND PRECAUTIONS]
- Clostridium difficile-associated diarrhea [see WARNINGS AND PRECAUTIONS]
Clinical Trials Experience
The following adverse reactions were reported from clinical trials:
Diarrhea, oral candidiasis (oral thrush), mouth ulcers, vomiting, nausea, stomach cramps, epigastric pain, heartburn, flatus, anorexia and pseudomembranous colitis. Onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment [see WARNINGS AND PRECAUTIONS].
As with other cephalosporins, reports of increased BUN and creatinine levels, as well as renal failure, have been received.
Cephalosporin-class Adverse Reactions
In addition to the adverse reactions listed above that have been observed in patients treated with cefazolin, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibacterials: Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, renal impairment, toxic nephropathy, aplastic anemia, hemolytic anemia, hemorrhage, hepatic impairment including cholestasis, and pancytopenia.
Read the entire FDA prescribing information for Cefazolin (Cefazolin and Dextrose for Injection)
Additional Cefazolin Injection Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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