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Cefazolin

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Cefazolin Injection

Cefazolin Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Cefazolin and dextrose for injection is used to treat many different kinds of bacterial infections. It is an antibiotic. Common side effects include pain, swelling, skin rash, or a hard lump where the injection was given, diarrhea, stomach pain, nausea, vomiting, loss of appetite, skin rash or itching, white patches or sores inside the mouth or on the lips, or vaginal itching or discharge.

The dose of cefazolin varies depending on the condition being treated and its severity. For mild infections, the recommended adult dose is 250 mg to 500 mg every 8 hours. For more severe infections the dose is 500 mg to 1 g every 6 to 8 hours. Cefazolin may interact with probenecid. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant before receiving this medication. Cefazolin passes into breast milk in very low concentrations. Consult your doctor before breastfeeding.

Our cefazolin and dextrose for injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Cefazolin FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

The following reactions have been reported:

Gastrointestinal: Diarrhea, oral candidiasis (oral thrush), vomiting, nausea, stomach cramps, anorexia and pseudomembranous colitis. Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment (see WARNINGS). Nausea and vomiting have been reported rarely.

Allergic: Anaphylaxis, eosinophilia, itching, drug fever, skin rash, Stevens-Johnson syndrome.

Hematologic: Neutropenia, leukopenia, thrombocytopenia, thrombocythemia.

Hepatic: Transient rise in SGOT, SGPT, and alkaline phosphatase levels has been observed. As with other cephalosporins, reports of hepatitis have been received.

Renal: As with other cephalosporins, reports of increased BUN and creatinine levels, as well as renal failure, have been received.

Local Reactions: Rare instances of phlebitis have been reported at site of injection. Some induration has occurred.

Other Reactions:Genital and anal pruritus (including vulvar pruritus, genital moniliasis, and vaginitis).

Read the entire FDA prescribing information for Cefazolin (Cefazolin and Dextrose for Injection) »

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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