"Hospitals in the U.S. continue to make progress in the fight against central line-associated bloodstream infections and some surgical site infections, according to a report issued today by the Centers for Disease Control and Prevention (CDC). "...
(sterile cefoperazone) for Intravenous or Intramuscular Use
To reduce the development of drug-resistant bacteria and maintain the effectiveness of CEFOBID and other antibacterial drugs, CEFOBID should be used only to treat infections that are proven or strongly suspected to be caused by bacteria.
CEFOBID® (sterile cefoperazone), formerly known as sterile cefoperazone sodium, contains cefoperazone as cefoperazone sodium. It is a semisynthetic, broad-spectrum cephalosporin antibacterial drug. Chemically, cefoperazone sodium is sodium (6R,7R)-7-[(R)-2-(4-ethyl-2,3dioxo-1-piperazinecarboxamido)-2-(p-hydroxyphenyl)- acetamido-3-[[(1-methyl-1H-tetrazol-5yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Its molecular formula is C25H26N9NaO8S2 with a molecular weight of 667.65. The structural formula is given below:
CEFOBID (sterile cefoperazone) contains 34 mg sodium (1.5 mEq) per gram. CEFOBID is a white powder which is freely soluble in water. The pH of a 25% (w/v) freshly reconstituted solution varies between 4.5–6.5 and the solution ranges from colorless to straw yellow depending on the concentration.
CEFOBID (sterile cefoperazone) in crystalline form is supplied in vials containing 1 g or 2 g cefoperazone as cefoperazone sodium for intravenous or intramuscular administration.
Last reviewed on RxList: 3/30/2015
This monograph has been modified to include the generic and brand name in many instances.
Additional Cefobid Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.