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Celontin

"About 1 out of 10 people has had a seizure. Do you know what to do if someone has a seizure near you? Read below to learn more.

About 1 out of 10 people has had a seizure. That means seizures are common, and one day you might need to help s"...

Celontin

Celontin Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Celontin (methsuximide) is used alone or in combination with other medications to treat absence seizures (also called "petit mal" seizures). It is an anti-epileptic (anticonvulsant) medication. Common side effects include drowsiness, dizziness, stomach/abdominal pain, loss of appetite, nausea, vomiting, weight loss, diarrhea, headache, or loss of coordination.

Dose of Celontin is individualized. A suggested dosage is 300 mg per day for the first week. Dosage may be increased at weekly intervals by 300 mg per day for the three weeks following to a daily dosage of 1.2 g. Celontin may interact with phenobarbital, phenytoin, cold or allergy medicine, sedatives, narcotics, sleeping pills, muscle relaxers, and medicine for depression or anxiety. Tell your doctor all medications and supplements you use. During pregnancy, Celontin should be used only when prescribed. It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding. Abrupt withdrawal of anticonvulsant medication may precipitate absence (petit mal) status.

Our Celontin (methsuximide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Celontin in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have a serious side effect such as:

  • signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), mouth sores, feeling very weak or tired;
  • signs of liver damage, such as nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • joint pain or swelling with fever, swollen glands, muscle aches, chest pain;
  • patchy skin color, red spots, or a butterfly-shaped skin rash over your cheeks and nose (worsens in sunlight);
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling; or
  • worsening of seizures.

Less serious side effects may include:

  • diarrhea, constipation;
  • stomach pain, nausea, weight loss;
  • dizziness, drowsiness, nervousness, confusion;
  • headache;
  • blurred vision; or
  • loss of balance or coordination.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Celontin (Methsuximide) »

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Celontin Overview - Patient Information: Side Effects

SIDE EFFECTS: Drowsiness, dizziness, stomach/abdominal pain, loss of appetite, nausea, vomiting, weight loss, diarrhea, headache, or loss of coordination may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A small number of people who take anticonvulsants for any condition (such as seizure, bipolar disorder, pain) may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor immediately if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior including signs of depression, suicidal thoughts/attempts, thoughts about harming yourself.

Tell your doctor immediately if any of these rare but very serious side effects occur: signs of infection (such as fever, persistent sore throat), aching swollen joints, rash on nose and cheeks, severe tiredness, easy bruising/bleeding, rapid breathing.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Celontin (Methsuximide)»

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Celontin FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Gastrointestinal System

Gastrointestinal symptoms occur frequently and have included nausea or vomiting, anorexia, diarrhea, weight loss, epigastric and abdominal pain, and constipation.

Hemopoietic System

Hemopoietic complications associated with the administration of methsuximide have included eosinophilia, leukopenia, monocytosis, and pancytopenia with or without bone marrow suppression.

Nervous System

Neurologic and sensory reactions reported during therapy with methsuximide have included drowsiness, ataxia or dizziness, irritability and nervousness, headache, blurred vision, photophobia, hiccups, and insomnia. Drowsiness, ataxia, and dizziness have been the most frequent side effects noted. Psychologic abnormalities have included confusion, instability, mental slowness, depression, hypochondriacal behavior, and aggressiveness. There have been rare reports of psychosis, suicidal behavior, and auditory hallucinations.

Integumentary System

Dermatologic manifestations which have occurred with the administration of methsuximide have included urticaria, Stevens-Johnson syndrome, and pruritic erythematous rashes.

Cardiovascular

Hyperemia.

Genitourinary System

Proteinuria, microscopic hematuria.

Body as a Whole

Periorbital edema.

Read the entire FDA prescribing information for Celontin (Methsuximide) »

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Celontin - User Reviews

Celontin User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Celontin sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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