"The U.S. Food and Drug Administration today approved a new use of Gleevec (imatinib) to treat children newly diagnosed with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL).
ALL is the most common type of pediatric "...
Cerubidine Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Cerubidine (daunorubicin) is used in the treatment of leukemia (blood cancer). It is a cancer (antineoplastic) medication. This medication is available in generic form. Common side effects include nausea, vomiting, constipation, diarrhea, and loss of appetite. This medication may cause urine to turn a reddish color. This is a normal, harmless effect of the drug and should not be mistaken for blood in the urine. Temporary hair loss is a common side effect. Normal hair growth should return after treatment has ended.
Dosage of Cerubidine is determined by a physician and the drug is administered in a clinical setting. Cerubidine may interact with cyclophosphamide, methotrexate, or "live" vaccines. Tell your doctor if you have had previous treatment with doxorubicin, doxorubicin liposomal, daunorubicin, daunorubicin liposomal, idarubicin, or mitoxantrone. Because there is a maximum amount of these medications that should be administered to an individual, you may not be able to use Cerubidine. Tell your doctor all medications and supplements you use. Cerubidine is not recommended for use during pregnancy. It may harm a fetus. If you become pregnant or think you may be pregnant, tell your doctor. Males and females using this drug should use birth control (e.g., birth control pills, condoms) during treatment; consult your doctor. It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breastfeeding while using this drug is not recommended.
Our Cerubidine (daunorubicin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Cerubidine in Detail - Patient Information: Side Effects
If you experience any of the following serious side effects from daunorubicin, contact your doctor immediately:
- an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection);
- congestive heart failure (difficulty breathing, fluid retention, chest pain);
- tissue or vein reactions near the site of administration;
- liver damage (abdominal pain, yellowing of the skin or eyes);
- nausea, vomiting, diarrhea, or loss of appetite;
- inflamation or sores inside the mouth, throat, or intestines;
- rash, itching, or hives;
- fever, chills, or other signs of infection; or
- increased levels of uric acid in the body (joint pain and stiffness).
Other, less serious side effects may be more likely to occur. Continue taking daunorubicin and talk to your doctor if you experience:
- temporary hair loss; or
- red colored urine for 1 or 2 days following a dose.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Cerubidine (Daunorubicin)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Cerubidine Overview - Patient Information: Side Effects
Nausea, vomiting, constipation, diarrhea, and loss of appetite may occur. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If these effects persist or worsen, tell your doctor or pharmacist promptly.
This medication may cause your urine to turn a reddish color. This is a normal, harmless effect of the drug and should not be mistaken for blood in your urine.
Temporary hair loss is a common side effect. Normal hair growth should return after treatment has ended.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: unusual bleeding/bruising (e.g., small red spots on the skin, black/bloody stools, bloody urine, vomit that looks like coffee grounds).
Pain or sores in the mouth and throat may occur. Brush your teeth gently/carefully, avoid using mouthwash that contains alcohol, and rinse your mouth frequently with cool water mixed with baking soda or salt. It may also be best to eat soft, moist foods.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), trouble breathing, severe dizziness.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Cerubidine (Daunorubicin)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Cerubidine FDA Prescribing Information: Side Effects
Dose-limiting toxicity includes myelosuppression and cardiotoxicity (See WARNINGS). Other reactions include:
Gastrointestinal:Acute nausea and vomiting occur but are usually mild. Antiemetic therapy may be of some help. Mucositis may occur 3 to 7 days after administration. Diarrhea and abdominal pain have occasionally been reported.
Read the entire FDA prescribing information for Cerubidine (Daunorubicin)
Additional Cerubidine Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.