May 25, 2017
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(acetylcysteine) Effervescent Tablets for Oral Solution


Acetylcysteine is an antidote for the treatment of acetaminophen overdose. It is the N-acetyl derivative of the naturally-occurring amino acid, cysteine. Acetylcysteine is a white crystalline powder that is freely soluble in water, alcohol, practically insoluble in chloroform and in ether with the molecular formula C5H9NO3S, a molecular weight of 163.2, and chemical name of N-acetyl-L-cysteine. Acetylcysteine has the following structural formula:

CETYLEV (acetylcysteine) Structural Formula Illustration

CETYLEV (acetylcysteine) effervescent tablets for oral solution contain 500 mg or 2.5 grams of acetylcysteine. The following are inactive ingredients: sodium bicarbonate, maltodextrin, lemon flavor, sucralose, peppermint flavor, and edetate disodium.

The amount of sodium in each tablet of CETYLEV is shown in Table 3.

Table 3: Amount of Sodium Per CETYLEV Tablet

Tablet Strength Sodium Bicarbonate (mg)* Sodium (mg) Sodium (mEq)
500 mg 320 mg 88 mg 3.8 mEq
2.5 grams 1600 mg 438 mg 19 mEq
*inactive ingredient

Last reviewed on RxList: 5/1/2017
This monograph has been modified to include the generic and brand name in many instances.

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