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Tylenol-Codeine

Drug Description
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TYLENOL® with Codeine
(acetaminophen and codeine phosphate) Tablets
Analgesic For Oral Use

DRUG DESCRIPTION

Each tablet contains:

No. 3 Codeine Phosphate........................................................................................... 30 mg

Acetaminophen..................................................................................................... 300 mg

No. 4 Codeine Phosphate............................................................................................60 mg

Acetaminophen..................................................................................................... 300 mg

Inactive ingredients: powdered cellulose, magnesium stearate, sodium metabisulfite† , pregelatinized starch, starch (corn).

Acetaminophen, 4'-hydroxyacetanilide, is a nonopiate, non-salicylate analgesic and antipyretic which occurs as a white, odorless, crystalline powder, possessing a slightly bitter taste. Its structure is as follows:

Acetaminophen structural formula illustration

C8H9NO2         M.W. 151.16

Codeine is an alkaloid, obtained from opium or prepared from morphine by methylation. Codeine phosphate occurs as fine, white, needle-shaped crystals, or white, crystalline powder. It is affected by light. Its chemical name is: 7,8-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol phosphate (1:1) (salt) hemihydrate. Its structure is asfollows:

Codeine structural formula illustration

C18H21NO3.H3PO4.½H2O         M.W. 406.37

† See WARNINGS

Brand Name: Tylenol-Codeine
Generic Name: Acetaminophen and Codeine
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