Activated charcoal with sorbitol has produced severe hypernatremic dehydration when used in excessive amounts in pediatric patients.^25,27

Aspiration of activated charcoal has been reported to produce airway obstruction and a limited number of fatalities have occurred.^28,29,30,31 Bronchiolitis obliterana resulting in death has developed several weeks after the aspiration of activated charcoal.³²

Gastrointestinal obstruction associated with the use of multiple dose activated charcoal therapy has been reported.³³ An overdose of carbamazepine was responsible for the antiperistaltic effects which led to bowel obstruction.

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