Two clinical trials supported by the National Institutes of Health (NIH) have compared the anti-PRP antibody responses to three Haemophilus b conjugate vaccines in racially mixed populations of children. These studies were done in Tennessee ¹⁶ (Table 1) and in Minnesota, Missouri and Texas ¹⁷ (Table 2) in infants immunized with ActHIB^® and other Haemophilus b conjugate vaccines at 2, 4 and 6 months of age. All Haemophilus b conjugate vaccines were administered concomitantly with Poliovirus Vaccine Live Oral and DTP vaccines at separate sites.

ANTI-PRP ANTIBODY RESPONSES IN 2-MONTH-OLD INFANTS NIH TRIAL IN TENNESSEE
GEOMETRIC MEAN TITER (GMT) (µg/ mL)
VACCINE	N*	Pre-Immunization		Post Second Immunization		Post Third Immunization		Post Third Immunization %>1.0µg/mL
PRP-T† (ActHIB® )	65	0.10		0.30		3.64		83%
PRP-OMP (PedvaxHIB®)	64	0.11		0.84		N/A		50%**
HbOC† (HibTITER® )	61	0.07		0.13		3.08		Brand Name: ActHIB Generic Name: Haemophilus b Conjugate Vaccine « Previous Clinical Pharmacology Next » Next: ActHIB - Patient Information » « Previous: ActHIB - Overdosage & Contraindications Bookmark this page: WebMD Resources Kids' Nutrition: Top Tips for Home and School Bedwetting Solutions: A Guide for Parents Natural Relief for Your Child's Allergies Overscheduled Families Do you run your kids from one activity to another, day after day? If so, you should take a minute to watch.See more WebMD Videos » Privacy Policy Parenting and Pregnancy Get tips for baby and you. Childhood ADHD: Help Your Child Shine Learn About a New, Long-Acting Treatment Know the Facts: A New, Long-Acting Treatment Engage Your Doctor: ADHD Discussion Guide ActHIB Drug Description Indications & Dosage Side Effects & Drug Interactions Warnings & Precautions Overdosage & Contraindications Clinical Pharmacology Patient Information Health Resources Attention Deficit Hyperactivity Disorder (ADHD) Common Cold Diaper Rash Childhood Immunization (Vaccination) Flu (Influenza) Drug News 2008 Election & Health Care on WebMD. Get Informed. NSAIDs No Help Against Alzheimer's Viagra Fights Muscular Dystrophy? Schizophrenia Has a New Shot Treatment View More » Search the Medical Dictionary for Health Definitions & Medical Abbreviations Updated & New News & Features Identify Your Drugs: Use the RxList Pill Identification Tool Add RxList Search to Your Website Google Subscribed Links & RxList RxList Home|Drugs & Medications A-Z List |Pill Identification Tool |Drug Medical Dictionary |Diseases & Conditions About RxList|Contact RxList|Terms & Conditions|Privacy Policy|Sponsor Policy|Site Map WebMD®|MedScape®|eMedicineHealth®|MedicineNet® Copyright © 2008 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.