45

* N=Number of Children

Antibody responses to diphtheria, tetanus and pertussis antigens were also measured in this trial. Post dose three antibody responses to all measured vaccine antigens were similar, within each study, when infants who received the combined vaccine were compared to infants who received whole-cell DTP and ActHIB^® separately. Interference with the antibody response to the pertussis component has been suggested with a DTP vaccine unlicensed in the US. ²⁰ Percentages of subjects achieving antibody titers over 1 µg/mL and GMT to PRP in 2-month-old infants following immunization with ActHIB^® combined with AvP DTP by reconstitution was similar when compared to infants who received DTP and ActHIB^® separately (84% versus 85% and 4.3 µg/mL versus 4.8 µg/mL). 14,18

TriHIBit^TM, ActHIB^® COMBINED WITH TRIPEDIA^® VACCINE BY RECONSTITUTION FOR BOOSTER DOSE Randomized comparative clinical trials demonstrated that the anti-PRP response achieved in 15 to 20 month old children after one dose of TriHIBit^TM, Tripedia^® and ActHIB^® combination vaccine, was similar to that achieved when the two vaccines were given concomitantly at different sites with separate needles and syringes (Table 4). ¹⁸ All children had received three doses of a Haemophilus b conjugate vaccine (HibTITER^® or ActHIB^®) and three doses of a whole-cell DTP vaccine prior to entry into this clinical trial.

ANTI-PRP RESPONSES IN 15 TO 20-MONTH-OLD CHILDREN FOLLOWING IMMUNIZATION With TriHIBitTM COMPARED TO ActHIB® AND TRIPEDIA GIVEN CONCOMITANTLY AT SEPARATE SITES
IMMUNOGENICITY
	Brand Name: ActHIB Generic Name: Haemophilus b Conjugate Vaccine « Previous Clinical Pharmacology Next » Next: ActHIB - Patient Information » « Previous: ActHIB - Overdosage & Contraindications Bookmark this page: WebMD Resources Kids' Nutrition: Top Tips for Home and School Bedwetting Solutions: A Guide for Parents Natural Relief for Your Child's Allergies Overscheduled Families Do you run your kids from one activity to another, day after day? If so, you should take a minute to watch.See more WebMD Videos » Privacy Policy Parenting and Pregnancy Get tips for baby and you. Childhood ADHD: Help Your Child Shine Learn About a New, Long-Acting Treatment Know the Facts: A New, Long-Acting Treatment Engage Your Doctor: ADHD Discussion Guide ActHIB Drug Description Indications & Dosage Side Effects & Drug Interactions Warnings & Precautions Overdosage & Contraindications Clinical Pharmacology Patient Information Health Resources Attention Deficit Hyperactivity Disorder (ADHD) Common Cold Diaper Rash Childhood Immunization (Vaccination) Flu (Influenza) Drug News 2008 Election & Health Care on WebMD. Get Informed. Schizophrenia Has a New Shot Treatment Kid Antipsychotics Might Lead to Weight Gain 'Abuse-Proof' OxyContin Nixed by FDA View More » Search the Medical Dictionary for Health Definitions & Medical Abbreviations Updated & New News & Features Identify Your Drugs: Use the RxList Pill Identification Tool Add RxList Search to Your Website Google Subscribed Links & RxList RxList Home|Drugs & Medications A-Z List |Pill Identification Tool |Drug Medical Dictionary |Diseases & Conditions About RxList|Contact RxList|Terms & Conditions|Privacy Policy|Sponsor Policy|Site Map WebMD®|MedScape®|eMedicineHealth®|MedicineNet® Copyright © 2008 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.