Hexalen (Altretamine) drug description - FDA approved labeling for prescription drugs and medications at RxList

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Hexalen

Drug Description

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WARNINGS
1. HEXALEN® should only be given under the supervision of a physician experienced in the use of antineoplastic agents.
2. Peripheral blood counts should be monitored at least monthly, prior to the initiation of each course of HEXALEN, and as clinically indicated (see Adverse Reactions).
3. Because of the possibility of HEXALEN-related neurotoxicity, neurologic examination should be performed regularly during HEXALEN administration (see Adverse Reactions).

DRUG DESCRIPTION

HEXALEN (altretamine), is a synthetic cytoxic antineoplastic s-triazine derivative. HEXALEN capsules contain 50 mg of altretamine for oral administration. Inert ingredients include lactose, anhydrous and calcium stearate. Altretamine, known, chemically as N,N,N',N',N",N",- hexamethyl-1,3,5-triazine-2, 4, 6-triamine, has the following structural formula:

Its empirical formula is C9H18N6 with a molecular weight of 210.28. Altretamine is a white crystalline powder, melting at 172° ± 1° C. Altretamine is practically insoluble in water but is increasingly soluble at pH3 and below.

Brand Name: Hexalen
Generic Name: Altretamine

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