Hexalen
OVERDOSE
No case of acute overdosage in humans has been described. The oral LD50 dose in rats was 1050 mg/kg and 437 mg/kg in mice.
CONTRAINDICATIONS
HEXALEN is contraindicated in patients who have shown hypersensitivity to it. HEXALEN should not be employed in patients with preexisting severe bone marrow depression or severe neurologic toxicity. HEXALEN has been administered safely, however, to patients heavily pretreated with cisplatin and/or alkylating agents, including patients with preexisting cisplatin neuropathies. Careful monitoring of neurologic function in these patients is essential.
Generic Name: Altretamine
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Hexalen
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