Table 2: Median ACR Component Scores in Study 1

Placebo/MTX

(n = 251)

Kineret^®/MTX
100 mg/day
(n=250)

Parameter (median)

Baseline

Month 6

Baseline

Month 6

Patient Reported Outcomes

   Disability index^a

1.38

1.13

1.38

1.00

   Patient global assessment^b

51.0

41.0

51.0

29.0

   Pain^b

56.0

44.0

63.0

34.0

Objective Measures

   ESR (mm/hr)

35.0

32.0

36.0

19.0

   CRP (mg/dL)

2.2

1.6

2.2

0.5