Aristospan 5 mg
Aristospan®
(triamcinolone hexacetonide injectable suspension, USP) 5 mg/mL Parenteral
NOT FOR USE IN NEWBORNS
FOR INTRALESIONAL ADMINISTRATION
NOT FOR INTRAVENOUS USE
DRUG DESCRIPTION
A sterile suspension containing 5 mg/mL of micronized triamcinolone hexacetonide in the following inactive ingredients:
Polysorbate 80 NF 0.20% w/v
Sorbitol Solution USP 50.00% w/v
Water for Injection qs ad 100.00% V
Hydrochloric Acid and Sodium Hydroxide, if required, to adjust pH to 4.0-8.0
Preservative:
Benzyl Alcohol 0.90% w/v
Chemically triamcinolone hexacetonide USP is 9α-Fluoro-11β,16α, 17,21- tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-(3,3- dimethylbutyrate). The molecular weight is 532.65. The structural formula is:
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The hexacetonide ester of the glucocorticoid triamcinolone is relatively insoluble (0.0002% at 25°C in water).
Generic Name: Triamcinolone Hexacetonide Injection 5 mg
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