Photosensitivity manifested by an exaggerated sunburn reaction has been observed In some Individuals taking tetracyclines. Patients apt to be exposed to direct sunlight or ultraviolet light should be advised that this reaction can occur with tetracycline drugs, and treatment should be discontinued at the first evidence of skin erythema. Concurrent use of tetracyclines with oral contraceptives may render oral contraceptives less effective. (See DRUG INTERACTIONS,) Patients should be Informed that demeclocycline hydrochloride tablets should be taken at least 1 hour before meals or 2 hours after meals (See DOSAGE AND ADMINISTRATION.) Unused supplies of tetracycline antibiotics should be discarded by the expiration date. Patients who are experiencing headache, dizziness, lightheadedness, vertigo, or blurred vision while on demeclocycline therapy, should be cautioned about driving vehicles or using hazardous machinery while receiving demeclocycline therapy. (See WARNINGS.) Patients should be counseled that antibacterial drugs, Including Declomycin (demeclocycline hydrochloride) Tablets, should only be used to treat bacterial Infections. They do not treat viral Infections (e.g., the common cold). When Declomycin (demeclocycline hydrochloride) Tablets are prescribed to treat a bacterial Infection, patients should be told that although it is common to feel better early In the course of therapy, the medication should be taken exactly as directed.

Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the Immediate treatment and (2) Increase the likelihood that bacteria will develop resistance and will not be treatable by Declomycin (demeclocycline hydrochloride) Tablets or other antibacterial drugs in the future.

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